I'm one of those strange people who has it and is pretty happy with it. There were a few hiccups in the beginning, but it's fine now. There were no drivers for my old HP printer, but it was due to be replaced anyway. It took a while for me to realise that the Ethernet port on my mother board wasn't recognised (solved by installing a Gigabit board), and the DVD drive would read discs but not burn them. Now all is good except for one thing. The TV recording and viewing software I got with my Pinnacle TV card is available only in 32-bit. They keep promising a 64-bit version, but I reckon it will never happen. Windows Media Centre isn't nearly as good.
Maybe it's bloody-mindedness, but I believe that if one has a 64-bit processor, one should ideally have a 64-bit OS to utilise its potential.